
The Technology
The technology addresses the limitations of previously available treatment methods. It is a less invasive cancer treatment method that does not directly damage healthy tissues and organs, unlike traditional radio- or chemotherapy. Instead, it works selectively on cancer cells that express a specific target antigen on their surface (e.g., CD19). This approach demonstrates significantly higher efficacy than antibody therapies by leveraging the high cytotoxic potential of natural effectors in the therapy—T lymphocytes.
The first successful clinical trials of CAR-T therapy marked significant medical breakthrough in cancer treatment in recent years. Following the administration of CAR-T cells, complete eradication of cancer cells was observed in B-ALL leukemias within a very short time, with some patients achieving complete remission after a single CAR-T dose.